_1691470490 20230808045450000 Rovedar Daryoushbabazadeh@gmail.com Rovedar Research in Biotechnology and Environmental Science Res. Biotechnol. Environ. Sci. 2980-7743 06 16 2023 2 2 Inga Badasyan R.V. Nushikyan With the Coronavirus disease pandemic in 2020-2023, salmonella distribution has gained great concerted attention since COVID-19 treatment and salmonellosis was conditioned by antibiotics.The present study aimed to investigate the incidence and clinical characteristics of Salmonellosis (salmonellosis gastroenteritis infection)  in Armenia during the COVID-19 pandemic, between 2020 and 2023, without age restrictions. The genus Salmonella was identified using biochemical tests and serological methods at Laboratories of Armenia. Near 100 stool samples ere cultured on SS agar and selenite aquatic agar. The study identified 57 infected cases with Salmonella species and the majority of infection was in Yerevan people (n = 37 patients). The oldest patient was 71 years old from the Stepanavan region. Common symptoms included high temperature, diarrhea, restraint, weakness, pus residue in stool, unformed stool, headache, and dizziness. Two children from the same family were infected with Salmonella during the study. The patients were treated with different antibiotics for 3-10 days, with rifampicin, cephalosporins (2nd and 3rd generation), and carbapenems being the most commonly administrated drugs. The antibiotic susceptibility index was determined using the EUCAST documents. After the antibiotic therapy, the patients' health was monitored for a month. Additionally, the study found the Extended Spectrum Beta-Lactamase (ESBL) enzymes in newborn, 10-year-old, and 33-year-old patients. 06 16 2023 30 34 https://creativecommons.org/licenses/by/4.0 10.58803/rbes.v2i2.12 https://rbes.rovedar.com/index.php/RBES/article/view/12 https://rbes.rovedar.com/index.php/RBES/article/download/12/39 https://rbes.rovedar.com/index.php/RBES/article/download/12/39 10.3389/fmicb.2020.592223 Lee Goldman MD, Salmonella infections (including enteric fever), 2020 10.1016/j.pedneo.2013.01.010 Mahon CR, and Lehman DC. Textbook of diagnostice microbiology. 6th ed. Elsevier; 2022. Available at: https://b2n.ir/x37858 10.1155/2016/4290506 10.1186/s12917-019-1867-z European Centre for Disease Prevention and Control. Salmonellosis. In: ECDC. Annual Epidemiological Report for 2020, Stockholm, October 2022 Mughini-Gras L, Chanamé Pinedo L, Pijnacker R, van den Beld M, Wit B, Veldman K, Bosh T, Franz E. Impact of the COVID-19 pandemic on human salmonellosis in the Netherlands. Epidemiol Infect. 2021 Dec 2;149:e254. doi: 10.1017/S0950268821002557. PMID: 36318161; PMCID: PMC8692841. 10.5578/mb.20229814 European Centre for Disease Prevention and Control. Salmonellosis. In: ECDC. Annual Epidemiological Report for 2020. Stockholm: ECDC; 2022 10.1080/21553769.2015.1051243 Darby J, and Sheorey H. Searching for Salmonella. Melbourne: Australian Family Physician; 2008; 37(10): 806-810. Available at: https://www.proquest.com/scholarly-journals/searching-salmonella/docview/216294848/se-2 10.1016/S0140-6736(05)67181-4 10.1016/j.tips.2005.09.005 10.1086/318457 10.1016/j.imlet.2017.07.006 10.1089/fpd.2014.1744 10.2807/1560-7917.ES.2022.27.22.2100918 Meina Yue, Di Liu, Xiaoyu Li, Shurui Jin, Xue Hu, Xinfeng Zhao, and Yidong Wu, Epidemiology, Serotype and Resistance of Salmonella Isolates from a Children’s Hospital in Hangzhou, Zhejiang, China, 2006–2021. 10.3390/ijms23169330 10.1017/S0950268821002557 10.1111/j.1600-0463.2004.apm11211-1213.x Moutaz A.W. Abdul Mounam, The Effect of Myrtus Communis Extracts on the Pathogenic Salmonella SPP. Isolated from Milk and Soft Cheese in Baghdad City, Azerbaijan Medical Journal, Volume 62, Issue 10, December, 2022 Jonathan D., Harsha Sh., Searching for Salmonella, Australian Family Physician,2008.